2005-10-18
DMLE+ release 2.3 is now available!

The latest release (2.3) is available here for Linux and Windows.

2005-10-18
Features of DMLE+ Release 2.3

This release mainly implements bug fixes.

2005-01-26
DMLE+ release 2.2 is available (it is recommended that you upgrade to 2.3)

The previous release (2.2) is available here for Linux and Windows.

2005-01-26
Features of DMLE+ Release 2.2

The DMLE+ program allows multipoint LD mapping using an arbitrary number of SNPs or microsatellite markers. DMLE+ implements Markov chain Monte Carlo (MCMC) methods to allow Bayesian estimation of the posterior probability density of the position of a disease mutation relative to a set of markers... more

2003-11-04
Registration no longer required to download DMLE+

Registration is no longer required to download new versions DMLE+. The previous release (2.14) is available here for Linux, Mac OS X and Windows.

2002-07-19
Features of DMLE+ Release 2.14

The DMLE+ program allows multipoint LD mapping using an arbitrary number of SNPs or microsatellite markers. DMLE+ implements Markov chain Monte Carlo (MCMC) methods to allow Bayesian estimation of the posterior probability density of the position of a disease mutation relative to a set of markers... more

2002-07-19
A primer on LD mapping

Linkage disequilibrium (LD) is a non-random association of alleles at loci that are in close proximity on a chromosome. LD mapping is based on the fact that a disease mutation arises on a particular chromosome and is initially exclusively associated with marker alleles present on that chromosome... more

2002-07-19
Agencies Supporting DMLE+ Development

DMLE+ software development is supported by grants from the CIHR and the NIH.